Biological Sciences Faculty

Roger F. Brown, Ph.D.

Professor Emeritus
Director, Biomaterials Laboratory

Research Interests

Biomaterials for bone repair and therapeutic applications

Development of bioactive glass coatings on titanium implants for enhanced bonding at implant site

Porous bioactive glass scaffolds for in vitro engineering of new bone tissue

Bioabsorbable composite materials for bone fracture fixation

Neutron-activatable glass microspheres for radiotherapeutic applications

Education

Colorado State University, Ft. Collins, B.S. Zoology, 1964

Colorado State University, Ft. Collins, Ph.D., Physiology, 1968

University of Pittsburgh School of Medicine, Pittsburgh, Postdoctoral training, 1968-71

Representative Publications

D.E Day, J. E. White, R.F. Brown and K.D McMenamin, "Transformation of borate glasses into biologically useful materials," Glass Technol.44(2): 75-81, 2003

S. Conzone, R. Brown, D. Day, and G. Ehrhardt, "In vitro and in vivo dissolution behavior of a dysprosium lithium borate glass designed for the radiation synovectomy treatment of rheumatoid arthritis," J. Biomed Mat. Res. 60: 260-268, 2002

Website

 

 

Ronald L Frank, Ph.D.

Associate Professor
Director, Laboratory of Plant Molecular Genetics

Research Interests

Identification of gene families using computer algorithms

Evolution and expression of gene families in plants

Structure and expression of phenylalanine ammonia lyase genes in soybean

Education

Houghton College, Houghton, New York, B.S. in Biology, 1978

Ohio State University, Columbus, M.S. in Genetics, 1981

Ohio State University, Columbus, Ph.D. in Genetics, 1985

Representative Publications

Lee L, Leopold JL, Frank RL. 2012. Exhaustive RT-RICO algorithm for mining association rules in protein secondary structure. Proceedings of the IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB) 2012, 260-266.

Lee L, Leopold JL, Frank RL. 2012. Protein secondary structure prediction using BLAST and exhaustive RT-RICO, the search for optimal segment length and threshold. Proceedings of the IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB) 2012, 35-42.

Lee L, Leopold JL, Frank RL. 2011. Protein secondary structure prediction using BLAST and relaxed threshold rule induction from coverings. Proceedings of the IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB) 2011, 7-14.

Lee L, Leopold JL, Kandoth C, Frank RL. 2010. Protein secondary structure prediction using RT-RICO: a rule-based approach. Open Bioinformatics J., 4:17-30.

Kandoth C, Ercal F, and Frank RL. 2010. A framework for automated enrichment of functionally significant inverted repeats in whole genomes. BMC Bioinformatics 11(Suppl 6):S20.

Lee L, Kandoth C, Leopold JL, Frank RL. 2010. Protein secondary structure prediction using parallelized rule induction from coverings. Int. J. Medicine and Medical Sci., 1(2):99-105.

Lee L, Leopold JL, Frank RL, Maglia AM. 2009. Protein Secondary Structure Prediction Using Rule Induction from Coverings. Proceedings of IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology 2009, 79-86.

Kandoth C, Frank RL, and Ercal F. 2008 Automation of an NSP-based (negative selection pattern) gene family identification strategy. In: Intelligent Engineering Systems Through Artificial Neural Networks. Vol. 18. (CH Dagli, DL Enke, KM Bryden, H Ceylan, M Gen, eds). ASME Press, Three Park Ave., New York, NY. 319-326.

Frank RL, Kandoth C, and Ercal F. 2008. Validation of an NSP-based (negative selection pattern) gene family identification strategy. BMC Bioinformatics 9(Suppl 9):S2.

Xu R, Wunsch DC, Frank RL. 2007. Inference of genetic regulatory networks with recurrent neural network models using particle swarm optimization. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 4(4):681-692.

Frank RL, Mane A, Ercal F. 2006. An automated method for rapid identification of putative gene family members in plants. BMC Bioinformatics 7(Suppl 2):S19.

Courses Taught

General Genetics (BIO 2223), Evolution (BIO 2233), Genomics (BIO 5333), Molecular Genetics (BIO 4323), Plant Biology (BIO 2383)

Website

 

Chen Hou, Ph.D.

Assistant Professor
Director, Laboratory of Animal Physiology

Research Interests

Life history tradeoffs, aging, and oxidative stress

Behaviors and physiology of social insects

Energetics of animal growth and reproduction

Mammalian respiratory physiology

Education

Sichuan University, Chengdu, China, B.S. in Physics, 1997

University of Missouri, Columbia, MO, M.S. in Physics, 2000

University of Missouri, Columbia, MO, Ph.D. in Physics 2005 

Representative Publications

N. Ferral, K. Holloway, M. Li, Z. Yin, and C. Hou*. 2016. Heterogeneous activity causes a nonlinear increase in the group energy use of ant workers isolated from their social environment. Insect Science In Press. (The first two authors are undergraduate students in Hou lab.)

R. Fan, G. Olbricht, X. Baker, and C. Hou*. 2016. Birth mass is the key to understand the negative correlation between lifespan and body size in dogs. Aging-U.S. In Press. (The 1st and 3rd authors are a visiting scholar and an undergraduate student respectively in Hou lab.)

K. Amunugama, L. Jiao, G. Olbricht, C. Walker, Y.-W. Huang, P. Nam, and C. Hou*. 2016. Cellular oxidative damage is more sensitive to biosynthetic rate than to metabolic rate: A test of the theoretical model on hornworms. Experimental Gerontology 82:73-80.(First two authors are graduate students in Hou lab)

 C. Hou. 2016. The similarity and difference between ant and human ultrasocieties: From the viewpoint of scaling laws. Behavioral and Brain Sciences 39:e101.

L. Jiao, K. Amunugama, M. Hayes, M. Jennings, A. Domingo, and C. Hou. 2015. Food restriction-induced alteration of energy allocation strategy in hornworms (Manduca sexta larvae).  The Science of Nature(former Naturwissenschaften) 102:40-50. (All the co-authors are students in Hou lab.)

C. Hou, K. Amunugama. 2015. On the complex relationship between energy expenditure and longevity: Reconciling the contradictory empirical results with a simple theoretical model. Mechanisms of Ageing and Development 149:50-64. (The co-author is a graduate student in Hou lab.)

M. Hayes, L. Jiao, T. Tsao, I. King, M. Jennings, and C. Hou. 2015. High temperature slows down growth in tobacco hornworms (Manduca sexta larvae) under food restriction. Insect Science 22: 424-430. (published online in 2014) (All the co-authors are students in Hou lab; the 1st author is an undergraduate student.)

 C. Hou. 2014. Increasing energetic cost of biosynthesis during growth makes refeeding deleterious. American Naturalist 184: 233-247.

 C. Hou. 2013. The energy trade-off between growth and longevity. Mechanisms of Ageing and Development 134:373-380. 

J. Shik, C. Hou (Co-first author), A. Key, M. Kaspari, and J.F. Gillooly. 2012. Toward a general life history model of the superorganism: predicting the survival, growth, and reproduction of ant societies. Biology Letters 8:1059-1062.

 C. Hou and M. Mayo. 2011. Pulmonary diffusional screening and the scaling laws of mammalian metabolic rates. Physical Review E 84:61915 (1-6).

 C. Hou, K. Bolt, and A. Bergman. 2011. A general model for ontogenetic growth under food restriction. Proc. Royal Society B 278:2881-2890.

 C. Hou, K. Bolt,and A. Bergman. 2011. A general life history theory for effects of caloric restriction on health maintenance. BMC Systems Biology 5:78.

 C. Hou, K. Bolt, and A. Bergman. 2011. Energetic basis of correlation between catch-up growth, health maintenance, and aging. J. Gerontology. A. Biol. Sci. 66A:627-638.

 C. Hou, S. Gheorghiu, V.H. Huxley, and P. Pfeifer. 2010. Reverse engineering of oxygen transport in the lung: Adaptive control from fractal networks. PLoS Comp. Biol. 6: e1000902. 

C. Hou, M. Kaspari, H.B. Vander Zanden, and J.F. Gillooly. 2010. The energetic basis of colonial living in social insects. Proc. Natl. Acad. Sci. of U.S.A. 107:3634-3638.

 C. Hou, W. Zuo, M.E. Moses, W. H. Woodruff, J. H. Brown, and G. B. West. 2008. Energy uptake and allocation during ontogeny.  Science 322:736-739. (Faculty of 1000 Biology Recommendations)

 

COURSES TAUGHT

Evolution (BIO 2233), Biology of Aging (BIO 3001), Mathmatical Modeling in Biology (Math 4097; Co-taught), Human Anatomy and Physiology II (BIO 3343)

Website

 

Yue-wern Huang, Ph.D.

Professor 
Director, Laboratory of Environmental Toxicology

Research Interests

Develop nanocarrier platforms to deliver biologically active molecules in vitro and in vivo for basic science research and biomedical applications

Investigate toxicity of nanomaterials to assess risk to human health; in particular, discover physical and chemical properties of nanomaterials that govern molecular mechanisms of nanotoxicity. Findings can be used for modeling and improvement of safer design of biocompatible nanomaterials

Evaluate effects of environmental estrogens such as pharmaceuticals, phytochemicals, and industrial chemicals on humans and the environment

Education

National Taiwan Normal University, Taipei, Taiwan, B.A., 1986

University of Wisconsin-Madison, Ph.D., Zoology, 1998

Representative Publications

2015. Betty R. Liu, Yue-Wern Huang, Robert S. Aronstam, and Han-Jung Lee. Comparative mechanisms of protein transduction mediated by cell-penetrating peptides in prokaryotes. International Journal of Molecular Sciences. Journal of Membrane Biology, 248(2):355-368. doi:10.1007/s00232-015-9777-x.

2015. Betty R. Liu, Hwei-Hsien Chen, Ming-Huan Chan, Yue-Wern Huang, Robert S. Aronstam, and Han-Jung Lee. Three arginine-rich cell-penetrating peptides facilitate cellular internalization of red-emitting quantum dots. Journal of Nanoscience and Nanotechnology 15(3):2067-2078.

2014. Yue-Wern Huang, Han-Jung Lee, Larry M. Tolliver, and Robert Aronstam. Delivery of nucleic acids and nanomaterials by cell-penetrating peptides: opportunities and challenges. BioMed Research International. Special Issue “Advances in Gene Delivery Systems”, volume 2015, article ID 834079, 16 pages. doi:10.1155/2015/834079.

2014. Microsugar Chang, Yue-Wern Huang, Robert S. Aronstam, and Han-Jung Lee. Cellular delivery of noncovalently-associated macromolecules by cell-penetrating peptides. Current Pharmaceutical Biotechnology, 15:267-275.

2013. Charles C. Chusuei, Chi-Heng Wu, Shravan Mallavarapu, Jeffrey G. Winiarz, Jong-Sik Moon, Robert S. Aronstam, and Yue-Wern Huang. Cytotoxicity in the age of nano: cell toxicity reflects certain physiochemical properties of fourth period of metal oxide nanoparticles. Chemico-Biological Interactions, 206:319-326.

2013. Betty R. Liu, Jeffrey G. Winiarz, Jong-Sik Moon, Shih-Yen Lo, Yue-Wern Huang, Robert S. Aronstam, Han-Jung Lee. Synthesis, characterization and applications of carboxylated and polyethylene-glycolated bifunctionalized InP/ZnS quantum dots in cellular internalization mediated by cell-penetrating peptides. Colloids and Surfaces B: Biointerfaces 111:162-170. (Y. H. and H. L. are corresponding authors.)

2013. Betty Revon Liu, Shih-Yen Lo, Chia-Chin Liu, Chia-Lin Chyan, Yue-Wern Huang, Robert S. Aronstam, Han-Jung Lee. Endocytic trafficking of quantum dots delivered by Pas nona-arginine cell-penetrating peptides in cells. doi:10.1371/journal.pone.0067100. PLOS ONE 8(6): e67100.

2013. Betty Revon Liu, Shih-Yen Lo, Chia-Chin Liu, Chia-Lin Chyan, Yue-Wern Huang, Robert S. Aronstam, Han-Jung Lee. Intracellular delivery of nanoparticles and DNAs by IR9 cell-penetrating peptides. doi:10.1371/journal.pone.0064205. PLOS ONE 8(5): e64205.

2013. Betty Revon Liu, Yue-Wern Huang, Huey-Jenn Chiang, and Han-Jung Lee. Mechanistic studies of intracellular delivery of proteins by arginine-rich cell-penetrating peptides in cyanobacteria. BMC Microbiology 13:57. doi:10.1186/1471-2180-13-57. (Highly accessed)

2013. Betty Revon Liu, Huey-Jenn Chiang, Yue-Wern Huang, Ming-Huan Chan, Hwei-Hsien Chen and Han-Jung Lee. Cellular internalization of quantum dots mediated by cell-penetrating peptides. Pharmaceutical Nanotechnology 1(2): 151-161.

2013. Ninu Madria, Nanditha Nair, Avinash Vadapali, Yue-Wern Huang, Simon Jones, and V. Prakash Reddy. Ionic liquid electrolytes for lithium batteries: Synthesis, electrochemical, and cytotoxicity studies. J. of Power Sources 234:277-284.

2013. Tso-Hao Tang , Chiung-Tan Chang , Hsiu-Jen Wang, Joshua D. Erickson, Rhett A. Reichard, Alexis G. Martin, Erica K. Shannon, Adam L. Martin, Yue-wern Huang, and Robert S. Aronstam. Oxidative stress disruption of receptor-mediated calcium signaling mechanisms. doi:10.1186/1423-0127-20-48. Journal of Biomedical Science 20:48. (Highly accessed)

2013. Betty R. Liu, Yue-Wern Huang, Huey-Jenn Chiang, and Han-Jung Lee. Primary effectors of transmembrane delivery of arginine-rich cell-penetrating peptides. Advanced Studies in Biology 5(1):11-25.

Courses Taught

Ecology (BIO 2263), Toxicology (BIO 4383), Nanobiotechnology (BIO 4666), Issues in Public Health (BIO 2372), Techniques in Applied and Environmental Biology (BIO 6273), Cell Biology (BIO 2213 team taught), Introduction to Environmental Science (BIO 1173)

Website

 

Melanie R. Mormile, Ph.D.

Professor

Special Assistant to the Provost for Faculty Affairs
Environmental Microbiology

Research Interests

Extremophilic Microorganisms in Hypersaline Environments

Bioenergy Production

Commodity Compound Production by Extremophilic Microorganisms

Antibiotic Resistance in Environmental Microorganisms

Education

University of Cincinnati, Cincinnati, B.S., 1985

University of Louisville, Louisville, M.S., 1988

University of Oklahoma, Norman, Ph.D., 1995

Recent Publications

Mormile, M.R.  2014.  Going from Microbial Ecology to Genome Data and Back:  Studies on a Haloalkaliphilic Bacterium Isolated from Soap Lake, Washington State.  Frontiers in Microbiology, 5: 628. doi:  10.3389/fmicb.2014.00628.

Paul, V.G., S.D. Minteer, B.L. Treu, and M.R. Mormile.  2014.  Ability of a haloalkaliphilic bacterium isolated from Soap Lake, Washington, to generate electricity at pH 11.0 and 7% salinity.  Environmental Technology, 35: 1003-1011.

Roush, D.W., D.A. Elias, and M.R. Mormile.  2014.  Metabolic capabilities of the members of the Order Halanaerobiales and their potential biotechnological applications.  Current Biotechnologies, 3: 3-9.

Begemann M.B., M.R. Mormile,O.C. Sitton, J.D. Wall, and D.A. Elias.  2012.  A streamlined strategy for biohydrogen production with Halanaerobium hydrogeniformans, an alkaliphilic bacterium. Frontiers in Microbiology 3:93. doi: 10.3389/fmicb.2012.00093.

Brown, S.D., M.B. Begemann, M.R. Mormile, J.D. Wall, C.S. Han, L.A. Goodwin, S. Pitluck, M.L. Land, L.J. Hauser, and D.A. Elias.  2011.  Complete genome sequence of the haloalkaliphilic, hydrogen producing Halanaerobium hydrogenoformans.  Journal of Bacteriology, 193: 3682-3683.

S.D. Findley, M.R. Mormile, A. Sommer-Hurley, X-C. Zhang, P. Tipton, K. Arnett, J.H. Porter, M. Kerley, and G. Stacey.  2011.  Activity-based metagenomic screening and biochemical characterization of bovine rumen protozoan glycosyl hydrolases. Applied and Environmental Microbiology, 77: 8106-8113.

Mormile, M.R., B-y. Hong, and K.C. Benison.  2009.  Molecular analysis of the microbial communities of Mars-analog lakes in Western Australia.  Astrobiology, 9: 919-930.

Courses Taught

Introduction to Biological Sciences (BIO 1201), Microbiology Lecture (BIO 3313), Environmental Microbiology (BIO 4313 & 6313), Astrobiology (BIO 3001 & 6423), Research Proposal Writing (BIO 6223), Bioremediation (BIO 6463), Advanced Microbial Metabolism (BIO 6513), Introduction to Geomicrobiology (BIO Experimental Course)

 

Dev K. Niyogi, Ph.D.

Associate Professor
Director, Laboratory of Freshwater Ecology

Research Interests

Effects of humanity on stream ecosystems

Role of biodiversity in controlling ecosystem processes

Nutrient uptake in streams and other aquatic systems

Education

Swarthmore College, Swarthmore, Pennsylvania, B.A, 1989

University of Colorado, Boulder, Ph.D., 1999

Representative Publications

Piggott, J.J., D.K. Niyogi, C.R. Townsend, and C.D. Matthaei. In press. Multiple stressors and stream ecosystem functioning: climate warming and agricultural stressors interact to affect processing of organic matter. Journal of Applied Ecology.

Kitto, J.A.J., D.P. Gray, J.S. Harding, H.S. Greig, and D.K. Niyogi. 2015. Meta-community theory and stream restoration: evidence that spatial position constrains stream invertebrate communities in a mine impacted landscape. Restoration Ecology. DOI: 10.1111/rec.12179.

Niyogi, D.K., J.S. Harding, and K.S. Simon. 2013. Organic matter breakdown as a measure of stream health in New Zealand streams affected by acid mine drainage. Ecological Indicators. 24:510-517.

Greenwood, M.J., J.S. Harding, D.K. Niyogi, and A.R. McIntosh. 2012. Improving the effectiveness of riparaian management for aquatic invertebrates in a degraded agricultural landscape: stream size and land-use legacies. Journal of Applied Ecology. 49:213-222.

Greig, H.S., D.K. Niyogi, K.L. Hogsden, P.G. Jellyman, and J.S. Harding. 2010. Heavy metals: confounding factors in the response of New Zealand freshwater fish assemblages to natural and anthropogenic acidity. Science of the Total Environment. 48:3240-3250.

Niyogi, D.K., J.M. Bandeff, C. Selman, and D.E. Menke. 2010. Nutrient flux, uptake, and transformation in a spring-fed stream in the Missouri Ozarks, USA. Aquatic Sciences. 72:203-212.

Niyogi, D.K., C.A. Cheatham, W.H. Thomson, and J.M. Christiansen. 2009. Litter breakdown and fungal diversity in a stream affected by mine drainage. Fundamental and Applied Limnology. 175:39-48.

Lear, G., Niyogi, D., J. Harding, Y. Dong, and G. Lewis. 2009. Biofilm bacterial community structure in streams affected by acid mine drainage. Applied and Environmental Microbiology. 75:3455-3460.

Niyogi, D.K., M. Koren, C. A. Arbuckle, and C.R. Townsend. 2007. Stream community structure along a catchment land-use gradient; subsidy-stress responses to pastoral development. Environmental Management. 39:213-225.

Niyogi D.K., K.S. Simon and C.R. Townsend. 2003. Breakdown of tussock grass in streams along a gradient of agricultural development. Freshwater Biology. 48:1698-1708

Niyogi D.K., W.M. Lewis Jr, and D.M. McKnight. 2002. Effects of stress from mine drainage on diversity, biomass, and function of primary producers in mountain stream. Ecosystems. 5:554-567

Courses Taught

Introduction to Environmental Science (BIO 1173), Biodiversity (BIO 1223), Ecology (BIO 2263), Field Ecology (BIO 2264), Global Ecology (BIO 4463), Freshwater Ecology (BIO 4363)

Website

 

Julie A. Semon, Ph.D.

Assistant Professor
Laboratory of Regenerative Medicine

Research Interests

Identifying molecular and therapeutic differences of mesenchymal stem cell subpopulations

Interactions of mesenchymal stem cells with extracellular matrix and endogenous cell populations

Trafficking and fate determination of mesenchymal stem cells

Education

Purdue University, West Lafayette, Indiana, B.S. 1998

Tulane University, New Orleans, Louisiana, Ph.D. 2008

Representative Publications

Semon, J.A., Maness, C., Zhang, X., Sharkey, S., Beutler, M.M., Shah, F.S., Pandey, A.C., Gimble, J.M., Zhang, S., Scruggs, B.A., Strong, A.L., Strong, T.A., Bunnell, B.A. Comparison of human adult stem cells from adipose tissue and bone marrow in the treatment of experimental autoimmune encephalomyelitis. Stem Cells Res Ther Jan 9;5(1):2 (2014).

Zhang, X., Bowles, A.C., Semon, J.A., Scruggs, B.A., Zhang, S., Strong, A.L., Gimble, J.M., Bunnell, B.A. Transplantation of Autologous Adipose Stem Cells Lacks Therapeutic Efficacy in the Experimental Autoimmune Encephalomyelitis Model. PLoS One Jan 21;9(1):e85007 (2014).

McFerrin, H.E., Olson, S.D., Gutschow, M., Semon, J.A., Sullivan, D.E., Prockop, D.J. Rapidly Self-Renewing Human Multipotent Multipotent Marrow Stromal Cells (hMSC) Express Sialyl Lewis X and Actively Adhere to Arterial Endothelium in a Chick Embryo Model System. PLoS One Aug 21;9(8):e105411 (2014).

Zhang, S., Danchuk, S.D., Bonvillain, R.W., Scruggs, B.A., Strong, A.L., Semon, J.A., Gimble, J.M., Betancourt, A.M., Sullivan, D.E., Bunnell, B.A. Interleukin-6 mediates the therapeutic effects of adipose-derived stem cells in lipopolysaccharide-induced acute lung injury. Stem Cells Jun;32(6):1616-28 (2014).

Courses Taught

Stem Cell Biology (BIO 5001), Tissue Engineering (BIO 5240 & 6240)

Website

 

Katie Shannon, Ph.D.

Associate Teaching Professor
Director, Laboratory of Cytokinesis

Research Interests

The temporal and spatial control of cell division

Budding yeast as a model to determine how cytokinesis is cell-cycle regulated.

Education

University of North Carolina-Chapel Hill, B.A., 1994

Harvard Medical School, Boston, MA , Ph.D., Cell and Developmental Biology, 2000

Representative Publications

Miller, D.P., Hall, H., Chaparian, R., Mara, M., Mueller, A., Hall, M.C., and Shannon, K.B.* (2015) Dephosphorylation of Iqg1 by Cdc14 regulates cytokinesis in budding yeast Molecular Biology of the Cell mbc.E14-12-1637; First Published on June 17, 2015; doi:10.1091/mbc.E14-12-1637

Stockstill, K.E., Park, J., Wille, R., Bay, G., Joseph, A. and Shannon, K.B.* (2013) Mutation of Hof1 PEST motif phosphorylation sites leads to retention of Hof1 at the bud neck and a decrease in the rate of myosin contraction. Cell Biology International Article first published online : 29 JAN 2013, DOI: 10.1002/cbin.10042

Shannon, K.B.* (2012) IQGAP family members in yeast, Dictyostelium, and mammalian cells. International Journal of Cell Biology Focus Issue on Cytoskeletal Proteins vol. 2012, Article ID 894817, 14 pages, 2012. doi:10.1155/2012/894817 PMCID: PMC3296274

Xu, Y., Liu B.R., Lee, H, Shannon, K.B., Winiarz, J.G., Wang, T. and Huang, Y.* (2010) Nona-arginine Facilitates Delivery of Quantum Dots into Cells via Multiple Pathways. Journal of Biomedicine and Biotechnology, vol. 2010, Article ID 948543, doi:10.1155/2010/948543, PMCID: PMC2965432

Liu, B.R., Li, J., Lu, S., Lee, H., Huang, Y.*, Shannon, K.B., and Aronstam, R.S. (2010) Cellular Internalization of Quantum Dots Noncovalently Conjugated with Arginine-Rich Cell-Penetrating Peptides. Journal of Nanoscience and Nanotechnology Vol. 10, 1–10 PMCID: PMC2999506

Stayton, I., Winiarz, J., Shannon, K., Ma, Y.* (2009) Study of Uptake and Loss of Silica Nanoparticles in Living Human Lung Epithelial Cells at the Single Cell Level. Analytical and Bioanalytical Chemistry. DOI 10.1007/s00216-009-2839-0

Park, S., Cable, A.E., Blair, J., Stockstill, K.E., Shannon, K.B.* (2009) Bub2 Regulation of Cytokinesis and Septation in Budding Yeast. BMC Cell Biology 10:43

Lin, W., Xu, Y., Huang, C., Ma, Y., Shannon, K.B., Chen, D. and Huang, Y.* (2008) In Vitro Oxidative Stress and DNA Damage Induced by Nano- and Micro-sized ZnO Particles in Human Lung Epithelial Cells. Journal of Nanoparticle Research Special Issue: Nanoparticles and Occupation Safety. DOI 10.1007/s11051-008-9419-7.

Ogony, J., Mathews, R., Anni, H., Shannon, K., and Ercal, N.* (2007) The mechanism of elevated toxicity in HepG2 cells due to combined exposure to ethanol and ionizing radiation. Journal of Applied Toxicology Published Online: Jul 13 2007 11:12AM in print J. Appl. Toxicol. 2008; 28: 345-355

Courses Taught

Introduction to Biological Sciences (BIO 1201), Cell Biology (BIO 2213), Senior Seminar (4010), Cancer Cell Biology (BIO 4353), Developmental Biology (BIO 5353)

Website

 

Mathew S. Thimgan, Ph.D.

Assistant Professor
Director, Laboratory of Sleep Biology

Research Interests

Biochemical and genetic factors of sleep regulation.

How sleep and wake transitions reflect health and aging.

Mitigating the consequences of sleep deprivation.

Physiological and molecular biomarkers of sleepiness in humans.

Education

University of California, Los Angeles, B.S., Microbiology, 1996

University of North Carolina, Chapel Hill, Ph.D., 2005

Representative Publications

Thimgan, M.S., Y. Suzuki, L. Seugnet, L. Gottschalk and P.J. Shaw, The Perilipin homologue, Lipid storage droplet 2, regulates sleep homeostasis and prevents learning impairments following sleep loss, PLoS Biology. 2010.

Olbricht, G.R., V.A. Samaranayake, S. Injamuri, L. Wang, C. Fiebelman, and M.S. Thimgan.  Modeling sleep and wake bouts in Drosophila melanogasterProceedings of the K-State  Conference on Applied Statistics in Agriculture. (April 27, 2014). Annual Conference on Applied Statistics in Agriculture. Paper 4. 2014

Donlea, J., M.S. Thimgan, Y. Suzuki, L. Gottschalk, and P.J. Shaw. Inducing sleep by remote control facilitates memory consolidation in DrosophilaScience. Jun 24;332(6037):1571-6, 2011.

Thimgan, M.S., C. Toedebusch, J. McLeland, S.P. Duntley, and P.J Shaw. Sleep apnea is associated with increased salivary markers of inflammation. Mediators of Inflammation. 2015:539627, 2015.

Thimgan, M.S., L. Seugnet, J. Turk, and P.J. Shaw. Identification of genes associated with resilience/vulnerability to sleep deprivation and starvation in DrosophilaSLEEP.  May 1;38(5):801-14, 2015.

Thimgan, M.S., J. Berg and A. Stuart. Comparative sequence analysis and tissue localization of members of the SLC6 family of transporters in adult Drosophila melanogaster. Journal of Experimental Biology 209(Pt 17):3383-3404, 2006.

Courses Taught

Human Anatomy and Physiology I (Bio 3333), Sleep: Function and Dysfunction (BIO 2243), Bioinformatics (BIO 5323), Advanced Sleep Biology (BIO 6001)

 

David J Westenberg, Ph.D.

Associate Professor

Faculty Athletics Representative

Laboratory of Microbiology

Research Interests

Rhizosphere microbiology

Antibacterial materials

Microbiology education

Education

Michigan State University, East Lansing, B.S. Microbiology and Public Health, 1982

University of California, Los Angeles, Ph.D. Microbiology and Molecular Genetics, 1991

Representative Publications

Yucelen, G. I., Connell, R. E., Terbush, J. R., Westenberg, D. J. and F. Dogan. 2015 Synthesis and immobilization of silver nanoparticles on aluminosilicate nanotubes and their antibacterial properties. J Applied Nanoscience, 2015-06-17

Westenberg, D.J. and Chang, A.L. 2015 “The Unseen Microbial World as a Tool for Learning Biology. The American Biology Teacher, 77:320-321.

Fumeaux, C., Bakkou, N, Kopciñska, J, Golinowski, W., Westenberg, D.J., Müller, P., and X. Perret.  2011 Functional analysis of the nifQdctA1y4vGHIJ operon of Sinorhizobium fredii strain NGR234 using a transposon with a NifA-dependent read-out promoter. Microbiology 157::2745-58.

D.J. Westenberg, 2007 B. japonicum, Agriculture and the Bacterium, BIOforum Europe, 11:16

Burken, J.G., Gilbertson, A.W. and Westenberg, D.J. 2007 Genetically Enhanced Rhizodegradation for Organic Contaminants In L. Newman and C. Reynolds., (eds.) Plant-Microbe Interactions for Environmental Remediation, Landes Bioscience, Georgetown, TX

D.J. Westenberg, 2002, Evidence for AHL autoinducer production by the soybean symbiont Bradyrhizobium japonicum. In: Finan et al. (eds.), Nitrogen Fixation: Global Perspectives, CABI Publishing, Oxford University Press, Cary, NC

V. Gulley and D.J. Westenberg, 2002, Regulation of the Bradyrhizobium japonicum sdh operon encoding succinate dehydrogenase, In: Finan et al (eds.), Nitrogen Fixation: Global Perspectives, CABI Publishing, Oxford University Press, Cary, NC

D. J. Westenberg and M. L. Guerinot, 1999, Succinate dehydrogenase (Sdh) from Bradyrhizobium japonicum is closely related to mitochondrial Sdh and is sensitive to the agricultural fungicide carboxin, J. Bacteriol.181:4676-4679

Courses Taught

Microbiology (BIO 3313) and Microbiology Lab (BIO 3319), General Genetics (BIO 2223), Pathogenic Microbiology (BIO 5313), General Virology (BIO 4493), Advanced Microbial Metabolism (BIO 6513), Biological Design and Innovation (BIO 3783), Communication Workshop for Pre-Health Professionals (PREMED 3010)

Website

 

Terry Wilson, M.S.

Associate Teaching Professor
Assistant Affiliate Director
Project Lead the Way Biomedical

Education

Southwest Missouri State University, Springfield, B.S. in Education, 1983

Southwest Missouri State University, Springfield, M.S. in Biology, 1993

Courses Taught

General Biology Lecture (BIO 1113) and Lab (BIO 1219), Principles of Biology (BIO 1213), Biodiversity (BIO 1223) and Lab (BIO 1229), Cell Biology Lab (BIO 2219)